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In normal tissues, the presence of elevated levels of ROS may facilitate the transformation of normal cells into cancer cells, thereby contributing to the development of cancer

10.4103/ijd.ijd_932_22 34

doi: 10.1038/s41416-020-0794-x 103 BranzoliFPontoizeauCTcharaLStefanoALKamounADeelchandDKet al

While these specific interventions have not been directly replicated for fertility restoration in mammalian models, the study mechanistically elevates ECM homeostasis as a central axis in aging